Endocrine Abstracts

Background: Concomitant thyroid cancer in patients with congenital thyroid dyshormonogesis (TD) is extremely rare and only few cases of differentiated thyroid cancer in patients with TD were reported in literature. We present the first case of anaplastic thyroid cancer (ATC) in woman with TD.Case: A 46-year-old female patient was referred to our hospital for thyroid surgery due to rapid tumor growing and compressive symptoms. The fine needle aspiration r...

Biotin is used in many hormone immunoassays as an immobilizing system as streptavidin binds biotin with high affinity. Recently, cases with spurious results from biotin interference have been increasing due to widespread use of vitamin supplements containing biotin. We report two cases of erroneously high total T3 levels caused by biotin interference.Case 1: A 88-year-old female who had total thyroidectomy for papillary thyroid cancer 10 years ago and ha...

Background: We evaluated the impact of the multifocality on post-lobectomy recurrence in patients with differentiated thyroid cancer (DTC).Methods: We analyzed 1,684 patients with DTC who underwent thyroid lobectomy from 2008 to 2015 using logistic regression models to calculate the relative risk on post-lobectomy recurrence.Results: Tumor diameter increased from 4.9 mm to 8.1 mm and the proportion of extrathyroidal extension (ETE)...

Object: The natural history and proper algorithm for follow-up testing of nonfunctioning pituitary adenomas (NFPAs) are not well known, despite their relatively high prevalence. The aim of this study was to suggest the optimal follow-up algorithm for NFPAs, based on the natural history.Methods: We followed up on 197 patients with NFPAs without any treatment (including surgery and radiation) at the time of detection, in a single center, between March 2000...